1 基本信息
姓名：满惠子
性别：女
职称：讲师
办公地点：明德楼803
Email：manhuizi@dlu.edu.cn
研究方向：生物智能制造，生物传感与成像分析，生物信息学
招生信息：
2 个人简介
满惠子，博士，讲师，先进设计与智能计算省部共建教育部重点实验室暨计算机辅助设计国家地方联合工程实验室教师，大连市青年才俊，研究方向为生物智能制造、生物传感与成像分析和生物信息学。迄今为止，已在Nano-Micro Letters、Biomaterials、Biosensors and Bioelectronics、Chinese Chemical Letters、Analytical Chemistry等国际著名期刊上发表SCI论文10余篇。
3 主要科研项目
1. 教育部供需对接就业育人项目，大连大学软件工程专业学生实践实训项目，项目编号：2023122841214，2023.12–2024.12，主持
2. 国家自然科学基金面上项目，22174009，基于四类呫吨染料母体的光激活探针，2022.01–2025.12，参与
3. 国家自然科学基金面上项目，21776037，酶标签融合蛋白的多色标记染料探针，2018.01–2021.12，参与
4. 国家自然科学基金青年项目，21804016，超分辨成像荧光染料分子的高通量筛选及发光机制定量研究，2019.01–2021.12，参与
5. 辽宁省自然科学基金面上项目，2024-MS-212，智能计算驱动的DNA存储编码设计，2024.09–2026.08，参与
6. 辽宁省科技计划联合计划(技术攻关计划项目)，2024JH2/102600064，基于NeuCube平台类脑计算模型的DNA存储编码研究，2024-12–2026-12，参与
4 主要研究成果 代表性论文
1. Man Huizi; Bian Hui; Zhang Xinfu; Wang Chao; Huang Zhenlong; Yan Yu; Ye Zhiwei; Xiao Yi; Hybrid Labeling System for dSTORM Imaging of Endoplasmic Reticulum for Uncovering Ultrastructural Transformations under Stress Conditions, Biosensors and Bioelectronics, 2021, 189: 113378. (中科院一区，IF: 12.545)
2. Man Huizi; Zhou Lin; Zhu Guanghao; Zheng Ying; Ye Zhiwei; Huang Zhenlong; Teng Xinru; Ai Chunzhi; Ge Guangbo; Xiao Yi; Super-resolution Imaging of Autophagy by a Preferred Pair of Self-labeling Protein Tags and Fluorescent Ligands, Analytical Chemistry, 2022, 94(43): 15057-15066. (中科院一区，IF: 8.008)
3. Liu Jun; Man Huizi; Chang Chen; Liu Qingyue; Yu Quanda; Wang Shiyu; Yang Peng; Xiao Yi; Liu Mingzhe; Fluorescent Probe-encapsulated Smart Nanohydrogel to Enhance Sensitivity toward Hydrogen Peroxide in Living Cells, Dyes and Pigments, 2023, 209: 110938. (共同一作，中科院二区，IF: 4.5)
4. Zhou Fuxing; Liu Xin; Xu Shujuan; Cui Shuang; Zhang Xiaokang; Man Huizi*; Wang Bin*; G-quadruplex-regulated Exonuclease Cooperative Hydrolysis Signal Transduction Strategy for Processing Molecular Temporal Information, New Journal of Chemistry, 2024, 48(42): 18320-18328. (共同通讯作者，中科院三区，IF: 2.7)
5. Liu Xiaokang; Wang Enlong; Man Huizi*; Zhou Shihua; Wang Yueping; RQVR: A Multi-exposure Image Fusion Network That Optimizes Rendering Quality and Visual Realism, Journal of Visual Communication and Image Representation, 2025, 107: 104410. (中科院四区，IF: 2.6)
6. Man Huizi; Jia Yan; Configurational Prediction of CYP2A6 Substrate Would Guide the Screening of Potential Substrate, Journal of Atomic and Molecular Sciences, 2018, 9: 46-52.
7. Ai Chunzhi; Man Huizi, Saeed Yasmeen; Chen Duchu; Wang Lihua; Jian Yizhoug; Computational Insight Into Crucial Binding Features for Metabolic Specificity of Cytochrome P450 17A1, Informatics in Medicine Unlocked, 2019, 15, 100172. (共同一作)
8. Li Jinlei; Shi Junpeng; Shen Jiangshan; Man Huizi; Wang Mingxi; Zhang Hongwu; Specific Recognition of Breast Cancer Cells in Vitro Using Near Infrared-emitting Long-persistence Luminescent Zn3Ga2Ge2O10:Cr3+ Nanoprobes, Nano-Micro Letters, 2015, 7(2): 138-145. (中科院一区，IF: 31.6)
9. Shi Junpeng; Sun Xia, Li Jinlei; Man Huizi; Shen Jiangshan; Yu Yanke; Zhang Hongwu; Multifunctional Near Infrared-emitting Long-persistence Luminescent Nanoprobes for Drug Delivery and targeted Tumor Imaging, Biomaterials, 2015, 37, 260-270. (中科院一区，IF: 12.8)
10. Liu Chuanhao; Zhou Lin; Xie Lijuan; Zheng Ying; Man Huizi; Xiao Yi; Forthrightly Monitoring Ferroptosis Induced by Endoplasmic Reticulum Stresses through Fluorescence Lifetime Imaging of Microviscosity Increases with a Specific Rotor, Chinese Chemical Letters, 2021, 33(5): 2537-2540. (中科院一区，IF: 9.4)
11. Yan Yu; Zhang Xiaodong; Zhang Xinfu; Li Ning; Man Huizi; Chen Lingcheng; Xiao Yi; Ratiometric Sensing Lysosomal pH in Inflammatory Macrophages by a BODIPY-rhodamine Dyad with Restrained FRET, Chinese Chemical Letters, 2020, 31(5): 1091-1094. (中科院一区，IF: 9.4)
12. Zhang Xiaodong; Ye Zhiwei; Zhang Xinfu; Man Huizi; Huang Zhenlong; Li Ning; Yi Xiao; A Targetable Fluorescent Probe for dSTORM Super-resolution Imaging of Live Cell Nucleus DNA, Chemical Communications, 2019, 55: 1951-1954. (中科院二区, IF: 6.222)
13. 牛淑云*; 满惠子;丁榆; Ni(Ⅱ)配聚物的合成、结构及光电性能研究, 辽宁师范大学学报（自然科学版）, 2014, 37(2): 216-220. (导师一作)
5 主讲课程
数据可视化（本科生）
软件安全（研究生）
